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Index > Protein center > Hsp90aa1(Gene name) > Rat
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  • Hsp90aa1 (Gene name),
  • Heat shock protein HSP 90-alpha (Protein name ),  HS90A_RAT from NCBI database.
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  • Gene name:
    Hsp90aa1(Hsp86;Hspca);
    Protein name:
    Heat shock protein HSP 90-alpha;
    Alternative:
    Heat shock 86 kDa(HSP 86;HSP86);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with AHSA1, FNIP1, HSF1, SMYD3 and TOM34. Interacts with TERT; the interaction, together with PTGES3, is required for correct assembly and stabilization of the TERT holoenzyme complex. Interacts with CHORDC1 and DNAJC7. Interacts with STUB1 and UBE2N; may couple the chaperone and ubiquitination systems.
    Function:
    Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
    Subcellular Location:
    Cytoplasm Melanosome
    Protein Attributes:
    Sequence length:
    733
    Sequence:
    50:
    MPEETQTQDQ | PMEEEEVETF | AFQAEIAQLM | SLIINTFYSN | KEIFLRELIS | 
    100:
    NSSDALDKIR | YESLTDPSKL | DSGKELHINL | IPNKQDRTLT | IVDTGIGMTK | 
    150:
    ADLINNLGTI | AKSGTKAFME | ALQAGADISM | IGQFGVGFYS | AYLVAEKVTV | 
    200:
    ITKHNDDEQY | AWESSAGGSF | TVRTDTGEPM | GRGTKVILHL | KEDQTEYLEE | 
    250:
    RRIKEIVKKH | SQFIGYPITL | FVEKERDKEV | SDDEAEEKEE | KEEEKEKEEK | 
    300:
    ESDDKPEIED | VGSDEEEEEK | KDGDKKKKKK | IKEKYIDQEE | LNKTKPIWTR | 
    350:
    NPDDITNEEY | GEFYKSLTND | WEEHLAVKHF | SVEGQLEFRA | LLFVPRRAPF | 
    400:
    DLFENRKKKN | NIKLYVRRVF | IMDNCEELIP | EYLNFIRGVV | DSEDLPLNIS | 
    450:
    REMLQQSKIL | KVIRKNLVKK | CLELFTELAE | DKENYKKFYE | QFSKNIKLGI | 
    500:
    HEDSQNRKKL | SELLRYYTSA | SGDEMVSLKD | YCTRMKENQK | HIYFITGETK | 
    550:
    DQVANSAFVE | RLRKHGLEVI | YMIEPIDEYC | VQQLKEFEGK | TLVSVTKEGL | 
    600:
    ELPEDEEEKK | KQEEKKTKFE | NLCKIMKDIL | EKKVEKVVVS | NRLVTSPCCI | 
    650:
    VTSTYGWTAN | MERIMKAQAL | RDNSTMGYMA | AKKHLEINPD | HSIIETLRQK | 
    700:
    AEADKNDKSV | KDLVILLYET | ALLSSGFSLE | DPQTHANRIY | RMIKLGLGID | 
    733:
    EDDPTVDDTS | AAVTEEMPPL | EGDDDTSRME | EVD
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    String:
    UniGene:
    Uniprot:
     
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    ELISA Kit for Rat Heat shock protein HSP 90-alpha
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    ELISA Kit for Rat Heat shock protein HSP 90-alpha
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    ELISA Kit for Rat Heat shock protein HSP 90-alpha
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    ELISA Kit for Rat Heat shock protein HSP 90-alpha
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    ELISA Kit for Rat Heat shock protein HSP 90-alpha
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    ELISA Kit for Rat Heat shock protein HSP 90-alpha
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    E0863c
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    96T
    CLIA Kit for Rat Heat shock protein HSP 90-alpha
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    U0863h
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    96T
    CLIA Kit for Rat Heat shock protein HSP 90-alpha
    Cat.:
    U0863p
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Heat shock protein HSP 90-alpha
    Cat.:
    U0863m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Heat shock protein HSP 90-alpha
    Cat.:
    U0863c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Heat shock protein HSP 90-alpha
    Cat.:
    U0863r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Heat shock protein HSP 90-alpha
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Heat shock protein HSP 90-alpha
    Cat.:
    U0863b
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    Please sign in first.
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    96T
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    Polyclonal Antibody for Rat Heat shock protein HSP 90-alpha
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    P0863Rb-m
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    Polyclonal Antibody for Rat Heat shock protein HSP 90-alpha
    Polyclonal Antibody for Rat Heat shock protein HSP 90-alpha
    Polyclonal Antibody for Rat Heat shock protein HSP 90-alpha
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    P0863Rb-h
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    Polyclonal Antibody for Rat Heat shock protein HSP 90-alpha
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    P0863Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Heat shock protein HSP 90-alpha
    Polyclonal Antibody for Rat Heat shock protein HSP 90-alpha
    Monoclonal Antibody for Rat Heat shock protein HSP 90-alpha
    Monoclonal Antibody for Rat Heat shock protein HSP 90-alpha
    Monoclonal Antibody for Rat Heat shock protein HSP 90-alpha
    Monoclonal Antibody for Rat Heat shock protein HSP 90-alpha
    Monoclonal Antibody for Rat Heat shock protein HSP 90-alpha
    Monoclonal Antibody for Rat Heat shock protein HSP 90-alpha
    Monoclonal Antibody for Rat Heat shock protein HSP 90-alpha
    Protein for Rat Heat shock protein HSP 90-alpha
    Cat.:
    R0863h
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Rat Heat shock protein HSP 90-alpha
    Protein for Rat Heat shock protein HSP 90-alpha
    Protein for Rat Heat shock protein HSP 90-alpha
    Protein for Rat Heat shock protein HSP 90-alpha
    Protein for Rat Heat shock protein HSP 90-alpha
    Protein for Rat Heat shock protein HSP 90-alpha

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    References
    1. 1.
      "Cloning of rat 86-kDa heat shock protein gene and promoter."
      Li C.W. , Chang M.T. , Lai Y. , Chang W.M. , Lai Y.K.
      Submitted (2001-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Brain.
    2. 2.
      "Cloning of full length cDNA of rat 86-kDa heat shock protein gene."
      Lai Y.R. , Chang M.D. , Chang W.M. , Su C.Y. , Lai Y.K.
      Submitted (2002-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Heart.
      tissue: Testis.
    4. 4.
      "Isolation and quantification of the heat shock protein 90 alpha and beta isoforms from rat liver."
      Langer T. , Fasold H.
      Protoplasma218:54-56(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-13
      strain: Sprague-Dawley.
      tissue: Liver.
    5. 5.
      Lubec G. , Afjehi-Sadat L.
      Submitted (2006-11) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 154-173; 329-339 AND 347-356;IDENTIFICATION BY MASS SPECTROMETRY
      strain: Sprague-Dawley.
      tissue: Spinal cord.
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